Fauci says data from NIH’s mix-and-match Covid vaccine booster trials will soon be ready


White House chief medical advisor Dr. Anthony Fauci said Tuesday that safety and efficacy data on pairing a primary regimen of Covid vaccines from one manufacturer with boosters from another could be available within the next two weeks.

Though the Centers for Disease Control and Prevention authorized Pfizer’s booster for seniors and the medically vulnerable Friday, only recipients of Pfizer’s first two doses are eligible for the third shot. But the National Institutes of Health is on the verge of concluding trials that mixed boosters and initial doses from Pfizer, Moderna and Johnson & Johnson, Fauci said at a White House Covid briefing.

“As with all things we do, they must be submitted to the FDA for their regulatory approval,” Fauci said of the so-called mix-and-match trials. “So you don’t want to get ahead of the FDA, but at least that’s where the data are right now.”

Data on Johnson & Johnson’s mix-and-match study could be ready within a week, while Pfizer’s trial might be completed by mid-October. Moderna’s mix-and-match study data is already available, Fauci added.



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